MK Dons will be without on-loan Andros Townsend because the Tottenham Hotspur winger played for Leyton Orient earlier in the competition.Midfielder Mark Randall, on loan from Arsenal, can play while Jude Stirling could make his first start this season.
Southampton will be without midfielder Dean Hammond (Achilles), while defender Jon Otsemobor is ineligible.
Radhi Jaidi is doubtful with an eye injury, with fellow veteran defender Graeme Murty (ankle) still sidelined.
Source: BBC Sport
Source: BBC Sport