Winger Lee Holmes is the only absentee following his recent ankle surgery but Adkins reported no new injuries following Monday's win at Dagenham.
Adkins is expected to make changes with one eye on Saints' League One promotion push.
Striker Lee Barnard has made two substitute appearances since recovering from a hernia operation and he could be named in the starting line-up for the first time since mid-November.
Frazer Richardson, Morgan Schneiderlin and David Connolly will also be in contention along with Jason Puncheon, who is back at St Mary's following his loan spell at Millwall.
Source: PA
Source: PA