Mauricio Pellegrino has given an injury update ahead of Saturday's game with Man Utd.
Matt Targett will miss the game at St Mary's with an ankle problem, but otherwise Pellegrino has a fully fit squad to select from.
“It is just Matt Targett, who has had some issues in his ankle, but the majority of them are ok," he said.
Virgil van Dyjk may be in line for a first team return after scoring for the U23's against Stoke on Monday.
“We’ll decide tomorrow," the boss revealed. "But every single week Virgil is important because he is getting better.
“After a long period of time without playing a game he is training well. It’s good news for us, because we need Virgil, like every single player in our squad.
“Virgil is a very important player for us. I think every single week he will improve, but at the same time he needs to train and play, because for me the best training session is playing games.”